YubNub cool keyboard commands in Firefox 

1. Use Firefox (what else)

2. Go to http://yubnub.org/ (opens in new window)

3. Right-click the input box

4. Click "Add a Keyword for this Search"

5. For the Name, enter "yubnub", and for the Keyword, enter "y"

6. Press [Save]

Now you can use YubNub directly from the Firefox address bar.
For example, try typing
y gim robert redl
into your address bar.

List of more cool commands:
http://yubnub.org/kernel/most_used_commands

Drag and Drop a link = it opens the link in a new tab
Drag and Drop Highlightet Text = Google search in a new tab
Drag and Drop an image = its downloaded

https://addons.mozilla.org/en-US/firefox/addon/6912

If you prefer using the mouse and minimizing its movements

try this cool Firefox Plugin:
http://optimoz.mozdev.org/gestures/